With the scant info you furnished:
What was the previous graphics card brand?
Did you perform a clean install of the drivers? Did you run DDU in safe mode to remove all remnants of the previous card? Clean Install AMD Graphics Drivers
Did you install the correct drivers?
Radeon™ RX 400 Series
Previous GPU was an Nvidia Geforce GTX 960
OS is Windows 10 x64
I had already uninstalled the Nvidia drivers prior to doing anything mentioned above.
My problem is that the drivers won't install period. In my "scant" info I mentioned that I'm getting error 173.
I'm going to reinstall Windows and see if that fixes my problem.