Very similar issue here. AMD Radeon R7 250 series (msi) on Windows 10. Restarts when opening games (steam). Periodically get Radeon Settings: Host application has stopped working and every application gets Application has been blocked from accessing graphics hardware. The screen also flashes/blinks every few seconds when any application is open.
If I remove all AMD software using DDU the screen is fine while utilizing the generic Microsoft display driver. If I reinstall the AMD driver, the problems return. I have made sure the OS is up to date and verified that .Net and Visual C is all good.
It looks from a search that this problem has been going on for years with AMD. What is the fix?