I use global scaling option( Select Display > Change the size of text, apps, and other items, and then adjust the slider) and have no problem with 16.12.1
You may try to Right-click the application(shortcut), select Properties, select the Compatibility tab, and then select the Disable display scaling on high DPI settings check box.
You may send report here
Good answer. I've just tried this out and turning off scaling for High DPI displays worked. The question is, why do I have to do this now when I didn't prior to reformatting. A default has changed somewhere, but at least now I can make this work.