I just installed an AMD RX 480 graphics card. When I use 16.12.1 drivers, the mouse cursor will turn into a box that is barely visible or black after the computer is on for an hour or two. When I switch back to 16.9.2 drivers the cursor is fine. When installing drivers I do use the AMD driver cleaning utility. With 16.9.2 the fans rarely start, and sometimes will spin to 100% for a minute or two then turn off and not turn on again. When temperatures reach the 50'sC the screen will turn into artifacts and the computer will turn off soon after.