I have a saphire r9 290 OC and a 3 monitor setup. Sometimes when i enable eyefinity something breaks and i cant use my computer if one of the monitors are connected with a certain cable. Now i used the quick setup and my screens kept connecting and reconecting, and the only thing i can do is to physicly plugg out my nr.1 monitor. If i plugg it back in my settup breaks again.
I have gotten around the problem by plugging different monitors in with different cables in the past. but im running out of variations of cables and monitors and it semes to be permanent, bacause when something breakes, not even reinstaling windows can fix it.
my nr.1 monitor is 1080p and uses hdmi. nr.2 is 1440p and uses DVI. and nr.3 is 1080p and uses dvi.