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We only test and validate up to four GPUs, so this configuration is not officially supported. I do not think it would work.
Thank you. I only know of one person that is able to get 5 gpus up and running in windows 10. Not in pentafire, just loading without crashing so that each gpu can be utilized for distributed computing, seti@home. Penta-Nano BOINC Server up and Running! - YouTube He had to disable automatic device scan/installation before manually installing older catalyst drivers.
We are trying to see if 6 is also doable.