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It could either be a faulty GPU or a driver issue. The HD4xxx series has reached peak optimisation and been moved to legacy status, there will not be any further driver updates for your product. More information available here.
The latest Catalyst WHQL driver for your system is 13.1 and is available here.
The latest Catalyst Beta driver for your system is 13.4 Beta and is available here.
I would recommend using DDU to sweep your system of AMD drivers, and then trying the drivers above to see if they resolve your issue.