I recently saw there was an update in the AMD Radeon Settings software. When I try to update and run the installer for it I'm prompted a generic "Operating system is not supported" error. I didn't have this problem when I originally installed all of the software a few weeks ago when I purchased my RX 480.
I'm running Windows 10 Pro 64-bit.
I guess it is possible the installer downloaded the 32bit OS version but I am not aware of a bug like that. Download the drivers manually and install that way.