You would need to post your full system spec and game settings please.
You can try changing the renderer to Vulkan or OpenGL for the game instead of DirectX.
i try but not fix
Have same issue with my pc ( i5-2500, TP67b+ , 16gb ram , rx460 2gb gigabyte )
running dota2 seems normal but sometime display being blackout and all reload,
game load with sound and etc. except graphical display