I am also using a Hdef Acer Monitor (2x resolution). The problem occurs whenever the computer is on (which is usually 24/7).
The quickest way to regain functionality would be a Windows System Restore, however you could try a system clean up and a fresh driver installation following the steps below, which may resolve the crashing.
1. Run the Windows self check tool to check scan and automatically repair any corrupt files found in Windows. There is a guide on how to do it here. What you need to do is run an elevated command prompt (elevated means run it as administrator) and type SFC /SCANNOW. This will generate a statement indicating if errors were found the Operating system and if they were fixable.
3. Update Windows. Install all available critical, recommended and optional updates. Often Netframework and Visual C are included in the recommended or optional updates Windows provides. Windows should always be fully up to date before installing our drivers!
4. Use DDU to sweep the system of AMD drivers in safe mode.
5. Install the latest Crimson 16.7.2 drivers once the above is completed and check to see if the issue is resolved.