Works great on my 290x.
Which AMD vidcard are you considering?
I have a AMD 380 and i have a lot of fps drops in urban areas, the settings are set to very high with 4X EQ antialiasing.
The performance you get is dependent on which card you plan on getting.
A card I would recommend you getting is the RX 480 as that card is sure to get you tremendous amounts of performance for the price and it is due 29th of June so just hold on for just a little longer and you can get a really nice card for just 199 USD (price is according to AMD and might vary from retailer to retailer, but it should be about that price.)
Hope my recommendation is good enough, cheers.