Whenever I try to play a game in Fullscreen, all I get is a Blackscreen that flickers white from time to time. I have no such problem in Borderless or Windowed, only in Fullscreen, regardless of which game I play ( I tried it with League of Legends, Terraria, GuildWars2, StarCraft2, Tales of Zestiria, MetalGearRising, DynastyWarriors 8 and many more)
Now this only happens on my main Monitor, a LG W3000H, which has a resolution of 2560 x 1600. On my second Monitor, a LG W2753VC, which has a resolution of 1900x1080, I have no problems at all and can run all of these games in Fullscreen.
I think the problem started around November 2015, after updating to Windows 10 and updating my AMD Drivers in the process. I kept updating my Drivers but it never helped. At the moment I am using the Crimson Edition 16.6.1 Hotfix.
Windows 10 64 bit version
Intel(R) Core(TM) i7 CPU K875 @ 2.93GHz
AMD Radeon HD 7990
Crimson Edition 16.6.1 Hotfix
Main Monitor: LG W3000H
Second Monitor: LG W2753VC