When I watch youtube video in fullscreen mode, the whole display will corrupted with random colors. This issue occurs after 18.104.22.168 and is still not fixed in 16.6.1.
The main cause for this issue is when in desktop/non-gaming mode, the VRAM is clocked at highest speed and refuse to drop clock, but the power/voltage is dropped to idle level causing the VRAM to work unstable.
In 16.6.1, even Overdrive is not able to down clock the VRAM(and can not overclock VRAM too).
Attached screenshot shows after applying the overclock, the VRAM stay at default clock speed.