It happens because probably you uninstalled your drivers with clean install. I had the same issue. Now i'm using 15.11.1 Beta for another reason(TDR crashes on R9 380) and i don't have this problem(because it's old fashioned Catalyst!). Check your Program Files\AMD folder for whether cccslim.exe is still exists.
I would recommend using System Restore to before this occurred, then uninstalling your current drivers normally via the AMD Installer, then updating to 16.5.3.