The issue you have described is mentioned in the release notes of our latest drivers.
- The Division™ may experience flickering in AMD Crossfire™ mode.
By running the game in Windowed mode you are disabling CrossFire and therefore, removing the flickering.
We hope to have a fix for this issue soon, stay tuned.
it happen on everygame now i can only play in window mode if i using fullscreen artifact show up how to fix this