When the game crashes, does it crash back to the desktop or does your machine bsod and reboot?
This sounds similar to an issue I am experiencing, try changing the CrossFire profile of the affected game to use the AFR Friendly rendering method and see if you still encounter the crash.
What power supply?
It always goes back to the desktop never had a BSOD. I've tried playing with the the profiles but there is no single profile that works all the time. On occasion it does load perfectly fine but try it again with the same settings and it fails.
I have an Antec Truepower 650W - I did think it could be a power issue but it does run some other games with no issues and I can run 3D Mark and other stress tests no problem.