OH man... you need to give more info. Link regarding this should be on main page.
I have a very similar problem.
Windows 10 64 Bit
16GB DDR 3 2133Mhz
Installed minimal Radeon Driver Package, removed and re-installed driver package.
Reboots. Tested each monitor individually.
"Detect" command in display = nothing detected.
"Scan for Hardware Changes" = nothing changes.
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