Hi, this is an issue I discovered after upgrading from Crimson 15.12 to Crimson 16.3.2 and the issue persists in Crimson 16.4.1
Namely that while Crossfire is active on the system, no cover indicators will show in XCOM:EW and the only way to get them back is to disable Crossfire completely. It is not enough just to disable it in the game profile. This is the latest available version of XCOM:EW, fully updated. Before upgrading to 16.3.2 and 16.4.1 the game worked without issues. I'm playing the game in native 1440p with all 3D setting set to max.
AMD HD7950 3GB (two identical cards in crossfire)
Desktop system/motherboard, Asus Crosshair V Formula Z
OS, Windows 10 64bit
Driver version installed, Radeon Software Crimson Edition 16.4.1
Display Devices, Dell U2713HM, 2560x1440 @60Hz, connected with DP
CPU, AMD FX8350
PSU, NitroX Nobility Series, 900W, Silver80plus
A workaround for this, which I stumbled upon (because it's completely unintuitive) is to run the executable (XComEW.exe) in Windows XP SP3 compatibility mode. That works, cover indicators are back without needing to disable Crossfire completely.