After using DDU to cleanly remove 16.1.1 I installed 16.2 and found that my second graphics card is no longer used in games nor does it appear in Windows Device Manager. In the Crimson System tab it numbers the GPUs of the 295x2 as #4 and #5 when they previously were #1 and #2 with my 290 as #3. Accessing the Crossfire settings in "Radeon Additional Settings" used to show a system wide Crossfire Enable/Disable toggle but that page is now blank. Any suggestions?
I have resolved this myself. In case others run into the same issue, this was fixed by unplugging my PC, hitting the power button a few times to drain any latent power and leaving it unplugged for 5-10 minutes. On the next boot up the system recognized the R9 290x and is working normally again.