I hear what you're saying, this used to be possible in CCC and Windows 7, you could create profiles and switch between them using hotkeys. I used to do this with my eyefinity setup and my TV. If I played an FPS with Mouse and Keyboard I would use my eyefinity setup, if I wanted to play with a controller I would switch to my TV. Super Battlestation - Album on Imgur <- check out this album from 3 years ago, I would switch output with Ctrl + Alt+ F4(Eyefinity), and Ctrl + Alt+ F5(TV)
The problem isn't the driver the problem is Windows 8+, MS changed the way the driver takes control of the display and Windows takes precedent.
There is a couple other things Windows 8+ broke as well. Sorry to say it but Microsoft shafted us.
When I was running win7 I had issues with it not working properly. Before win7 I was running multiscreens but a different setup and found the same issues with presets not saving everything.
Thanks for letting me know your thoughts. Seems like games and OS's are the same in the regard to "improvements" not always being good.