I am running a <6 month old 295X2, with two displays, the first is an Acer X341CK, the second is a Samsung U28D590D. Up until this morning, they both functioned perfectly. They are both plugged directly in to the video card via Display Port to Mini Display Port cables, with no adapters or daisy chains. Upon starting my computer today, during POST they both functioned normally, they both displayed the Windows logo normally, but once windows loaded, the Acer lost signal and the Samsung was set to primary. Unplugging the Samsung made the Acer turn on again and function normally. Unplugging the Acer had no effect on the Samsung and it functioned normally. When both are plugged in, regardless of which ports are used, regardless of whether the PC is powered on or off when they are plugged in, and in what order they are plugged in, once Windows loads, the Acer loses signal. While both are plugged in, Windows constantly detects a second monitor at a tiny resolution and then loses it again. I have tested all the display ports with both monitors, and they all function individually. Enabling and disabling Crossfire has no effect. Gaming functions completely normally, with the same performance I have always seen. System specs are listed below.
ASUS Maximus VII Formula
AMD Radeo Gamer Series 2133MHz DDR3, 2x8GB
Sapphire Radeon R9 295X2
Intel 730 Series 240GB SSD w/ Windows 8.1 x64
Seagate 3TB HDD
Cooler Master Silent Pro Gold 1000W PSU
Display 1: Acer X341CK
Display 2: Samsung U28D590D
There is no overclock on anything.