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Will AMD R9 M395X on an iMac work with Adobe Premiere Pro CC 2015?  Are there any issues to know about?

Question asked by kseichter on Oct 21, 2015

I am considering a big purchase of upgrading to an iMac to primarily do video editing in Adobe Premiere Pro.  The iMacs only come with the AMD R9 300 series and when I asked Adobe about this, because it's not listed on their compatible devices list, they claim there are problems that AMD and Apple need to fix.  Then when I went to the apple store the head guy at the genius bar had not heard anything about it and he said they usually find out stuff like that fairly quickly.  So now I am reaching out to AMD to either confirm or deny any problems with this setup before I lay down over 4k in a new computer.