It's been happening to me ever since the 12.x drivers, where clicking on different tasks will cause the interface to "black out" sometimes, fixed by dragging it off screen and back. I haven't seen any threads on it, so I imagine it's probably my system needing a fresh install of Windows (it's been 5 years).
Nah happens to me too sometimes. It happened before in some earlier CCC versions, but I can't seem to recreate the issue, so I have no idea what's related to the problem. It doesn't appear to cause issues besides the 'blacking out' though.