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Most of the latest inux distributions come with NMI watchdog enabled.
Oprofile and NMI use the same interrupt and hence require NMI watchdog to be disabed for profiling.
For some of the RHEL distributions, the NMI watchdog gets re-enabled though we disable it and hence you are forced to run this "echo 0 > /proc/sys/kernel/nmi_watchdog" command.
The best way to overcome is add "nmi_watchdog=0" at the end of your kernel boot present in "/boot/grub/menu.lst".