A DDR5 motherboard with DDR4 memory? 🤔 GPU disabling might indicate a power failure to gpu.
Remove all OC (cpu,ram,gpu etc), reseat gpu (can also try different pcie slot if possible) and reattach all psu power cables (including AC power), make sure that all fans are spinning and temperatures ok and try again. On that cpu the Intel spec memory frequency is max 3200MHz and running it higher like 3600MHz (OC) might lead to problems so disable xmp for testing. Also make sure you have the memory sticks in the right slots according to manual and only have keyboard mouse and one display attached for testing.
If still getting the issue after this and fresh driver install (or even windows install) I would consider hardware failure of psu, motherboard or even gpu. Best way to make sure is by replacing these one by one with good working parts and seeing if problem is fixed.
Check all motherboard capacitors if leaked/swollen: swollen capacitor at DuckDuckGo. Leaked or badly swollen caps on the motherboard means it's probably defect but no leaked caps doesn't mean it can't be defect. Broken motherboard often means it's time to change the psu too.
If motherboard looks fine and PSU is bad quality or very old I would replace that first. Then I would replace the motherboard if psu doesn't fix it... or if motherboard very old but psu good quality or new then I would consider the motherboard first. I haven't had any gpu's failing on my use but I guess it's possible.
It could also be worth it to take system to a computer fixing place as they have spare parts to test on and maybe could figure out what's wrong before you making any purchase.
