I play many games on my computer and have recently upgraded to a Radeon RX 580. Some games play fine. The games that do not play well all have the same issue. Cinematics run fine, but once actual gameplay begins the monitor loses signal and goes into sleep mode. This occurs on two completely different monitors. I have done everything suggested to troubleshoot this issue, but nothing has resolved it. The main game that has the issue is COD: WWII. Below is all the system info on my updated RX 580.
Radeon Software Version - 18.2.1
Radeon Software Edition - Adrenalin
Graphics Chipset - Radeon RX 580 Series
Memory Size - 8192 MB
Memory Type - GDDR5
Core Clock - 1380 MHz
Windows Version - Windows 10 (64 bit)
System Memory - 16 GB
CPU Type - Intel(R) Core(TM) i7-7700K CPU @ 4.20GHz
Radeon Settings Version - 2018.0131.1849.33856
Driver Packaging Version - 17.50.17.03-180131a-323831C-RadeonSoftwareAdrenalin
Provider - Advanced Micro Devices, Inc.
2D Driver Version - 8.1.1.1634
Direct3D® Version - 9.14.10.01316
OpenGL® Version - 6.14.10.13506
OpenCL™ Version - 23.20.15017.3010
AMD Mantle Version - 9.1.10.0237
AMD Mantle API Version - 102400
AMD Audio Driver Version - 10.0.1.6
Vulkan™ Driver Version - 2.0.1
Vulkan™ API Version - 1.0.65
Graphics Card Manufacturer - Powered by AMD
Graphics Chipset - Radeon RX 580 Series
Device ID - 67DF
Vendor ID - 1002
SubSystem ID - 3417
SubSystem Vendor ID - 1462
Revision ID - E7
Bus Type - PCI Express 3.0
Current Bus Settings - PCI Express 3.0 x16
BIOS Version - 015.050.002.001
BIOS Part Number - MS-V34113-F1
BIOS Date - 2017/08/28 22:54
Memory Size - 8192 MB
Memory Type - GDDR5
Memory Clock - 2000 MHz
Core Clock - 1380 MHz
Total Memory Bandwidth - 256 GByte/s
Memory Bit Rate - 8.00 Gbps
2D Driver File Path - /REGISTRY/MACHINE/SYSTEM/ControlSet001/Control/Class/{4d36e968-e325-11ce-bfc1-08002be10318}/0001