I recently got myself a copy of DMC4E , but when i want to load the game all i can do is sit in the menu. When i try to start the game it just crashes with a black screen.
I have seen many complaints of older games not running well and in some case at all with the new Navi architecture. I wish I had something for you to try.
You might want to also contact AMD support about the issue: https://www.amd.com/en/support/contact-email-form