Is really a boring bug, apparently has connection to the last update of Windows 10,
sometimes the problem is solved by putting in window mode, almost always works
Try disable the full screen optimization of windows 10, this can solve. There is a program
that does this, but I have not fully tested.
CompatibilityManager | Windows app for bulk editing compatibility settings.
Many people are with the same problem, in reddit some have said that installing an
older version of windows 10 solved.
https://www.reddit.com/r/buildapc/comments/8il7kc/ryzen_5_2400g_color_profiles_problem/
I hope this helps, good luck.