I've noticed that whenever I launch Steam VR, my graphics drivers seem to get broken or corrupted. I am no longer able to adjust multi-monitor layout, display resolution, refresh rate, or orientation in Windows. Those options are either greyed out, or in the case of the refresh rate, only have one option. I am also unable to adjust display resolution or fullscreen mode in any game. The only way to fix this that I have found is to totally uninstall the graphics drivers and then reinstall them. I'd very much like to not have to do this every time I want to play a VR game.
I have an RX 6800 on the latest drivers (although this has been happening for years)