So recently i got my Ryzen 5 3400g with Vega 11, and today i have updated it to Adrenaline 2020 the latest version, i have noticed many thing, first, the overlay doesn't work in Destiny 2, second AMD Radeon Software won't open after running the game and after i shutdown the game it won't start
i have faced this issue with the previous one and i though it needs a clean installation so i did that, removed the driver using DDU and trying again with AMD Cleanup Utility and same issue
it just keep it like this without open or anything
Try toggling Adaptive sync on your monitor. My overlay will only work while gaming in fullscreen on drivers 19.12.X after doing this fix on my LG 27GL850. You have to disable then enable adaptive sync on your monitor at least my monitor enables this this fixes the overlay to work in full screen games.
I am about to try the latest 20.1.1 driver now but I'm not sure why this issue wasn't listed on the known or fixed issues. I created a bug report with AMD through the link in Radeon settings.