50/50 its not AMDs fault
most likely it has to do with the newish Windows10 change in how Hardware is "spoken" to
try to reinstall your windows - than latest drivers etc - test again
try to clean your gpu and use it with AMD default clocks (reference stock clocks)
do you have a good PSU or a china-cracker? are all cables correct
GPU is clean, no dust on fans and heat sink, it is not overheating. My PSU is XFX TS 550W (P1-550S-XXB9), both 6+2 and 6 Pin are connected to the card. Tried running GPU on stock 1244MHz clock but made no difference.
I just removed 18.3.4 using ddu in safe mode and installed 17.11.1 (game was working fine on this drivers before Windows reinstall). Played it without crashes for nearly an hour. I even overclocked GPU to 1440MHz and memory to 2000MHz.
try any driver before 18.2.1 - because they changed HWacc in that driver